Suxamethonium Sensitivity

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منابع مشابه

Analysis of suxamethonium sensitivity following termination of pregnancy.

The cholinesterase genotypes in the majority (25/35) of patients with suxamethonium sensitivity following termination of pregnancy are heterozygotes with an E1a gene. Twelve of these patients have the genotype E1uE1a. The reported duration of apnoea is minimal in the heterozygotes lacking the E1a gene (about 5-10 min) and maximal in the homozygotes E1aE1a (about 35 min). With few exceptions, th...

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Familial Sensitivity to Suxamethonium Due to Atypical Pseudocholinesterase.

A simple apparatus which can deliver a painful electric shock to the subject for aversion therapy is described. It has advantages over nausea-producing drugs, particularly in allowing the patient to treat himself even at home. The use of the apparatus is illustrated by cases of fetishism, obsessional ruminations, smoking, writer's cramp, and alcoholism. Technical details are given of the compon...

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Goodbye suxamethonium!

No drugs in anaesthesia are more problematic than suxamethonium. Yet, no drugs have survived as suxamethonium does in spite of crisis after crisis, and attempt after attempt at its replacement. For decades, suxamethonium has taught us neuromuscular pharmacology and provided us with an encyclopaedia of side effects, while benefiting millions and millions of our anaesthetised patients. With the a...

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Suxamethonium-induced myalgia.

Sir,—I read with interest the paper by Kahraman and colleagues on the effect of i.m. diclofenac on suxamethonium-induced myalgia [1]. Diclofenac, administered i.m. to conscious patients, is painful and has a tendency to cause sterile abscesses. Its use to ameliorate suxamethonium myalgia could be a case of a "remedy worse than the disease". Pretreatments have been tried previously but all have ...

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Hexafluorenium extension of suxamethonium block.

Clinical trials of the effectiveness of hexafluorenium (Mylaxen), as an extender of suxamethonium block, have been conducted in 645 administrations of halothane. No serious complications which could be attributed to the drug were encountered. Histamine release after the administration of hexofluorenium was not observed. In view of the extreme efficacy and the apparent safety of the method descr...

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ژورنال

عنوان ژورنال: BMJ

سال: 1964

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.5381.501